Research Group on Drug Absorption.

 

Pharmacy and Pharmaceutical Technology section. School of Pharmacy. UMH

English / Spanish

News and Links of interest


 

 

Mission

Group Research and personal contributions

Competence
Projects
Research Report
Facilities

Team

Professors
Research Students
Staff

Teaching activities

Collaborations

 

mbermejo@umh

 

Areas of competence

  • Passive and active intestinal absorption.
  • Barriers against intestinal absorption of xenobiotics.
  • Influence of natural and synthetic surfactants on intestinal absorption.
  • Oral Bioavailability and Pharmacokinetics.
  • Computer modelling and simulation of ADME processes.
  • Physicochemical characterization:
    • Partition coefficient determination
    • Solubility
    • Dissolution testing

Techniques

Surgical procedures in rat:

  • In situ perfussion methods : stomach, small intestine and colon.
  • permanent jugular cannulation
  • bile duct cannulation

Analitical Techniques:

  • HPLC: UV and Fluorescence detection

Cell culture methods: Caco-2; MDCK; MDCK-Mdr1

·         Permeability experiments

·         Characterization of transport mechanism